Copovidone Pharmaceutical Excipients with Many Uses

Copovidone Pharmaceutical Excipients with Many Uses

SUNVIDONE ® VA Synonyms: Copovidone;Copolyvidone; PVP/ VAc CTFA/INCI:VP/VA copolymer CAS No.: [25086-89-9] Trade Name: Sunvidone ® VA SUNVIDONE ® VA is a vinylpyrrolidone-vinyl acetate copolymer that is soluble both in water and in alcohols. It is used in the pharmaceutical industry as binders,...
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Product Details

SUNVIDONE® VA


Synonyms: Copovidone;Copolyvidone; PVP/ VAc

CTFA/INCI:VP/VA copolymer

CAS No.: [25086-89-9]

Trade Name: Sunvidone® VA

SUNVIDONE® VA is a vinylpyrrolidone-vinyl acetate copolymer that is soluble both in water and in alcohols.

It is used in the pharmaceutical industry as binders, granulating agents, retarding agents and film.

forming agents in drugs.


SPECIFICATION

SUNVIDONE® VA meets the requirements of the latest USP/NF, Ph.Eur. and JPE

Appearance of solution (10%)

BY5, B5 min.

Heavy metals

20ppm max

Aldehydes

500ppm max.

Loss on drying

5.0% max

Peroxides

400ppm max.

sulphated ash

0.1% max

Hydrazine

1ppm max.

K value

25.2-30.8

Monomers

0.1% max.

Ethenyl acetate

35.3%-42.0%

Impurity A

0.5% max.

Nitrogen

7.0%-8.0%


CHARACTERISTICS

White or slightly yellowish, free-flowing powder with a faint characteristic odor and practically no taste.

Sunvidone® VA readily dissolves in all hydrophilic solvents. Solutions of more than 10% concentration can be prepared in: water; ethanol; isopropanol; methylene chloride; glycerol; propylene glycol; It is less soluble in: ether; cyclic, aliphatic and alicyclic hydrocarbons.


APPLICATIONS

• Binder for tablets and granules

Dry binder for direct compression

Wet granulation

Sunvidone® VA is an excellent binder for tablets and granules.

Between 2% and 5%, as a proportion of the final weight of the

preparation, is usually used.

• Film-coating

Sunvidone® VA forms films that are soluble at all pH values.

• Subcoating

Sunvidone® VA is used in sugar-coating to improve the

• Sugar-coating

adhesion of the coating to the surface of the tablet core and to

• Sprays

increase the capacity of the coating solution for pigments and

• Controlled-release preparations

improve their dispersibility.


PACKAGES                                      20KG or 25KG net in fiber drum or PP drum

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If you're looking for copovidone pharmaceutical excipients with many uses, please be free to place orders with our factory. We also support customized production for the famous brands' products. And if you need, the free sample is also available for quality checking.

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