Pharmaceutical Excipient Croslinked Polymer Crospovidone

Pharmaceutical Excipient Croslinked Polymer Crospovidone

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Product Details

We purpose to create a lot more price for our prospects with our rich resources, innovative machinery, experienced workers and great products and services for OEM Manufacturer for VP/VA copolymer solution, Povidone-Iodine, Dry binder. We've customers from more than 20 countries and our reputation has been recognized by our esteemed customers. Our company has standardized and professional production management processes from the conception, production and processing, quality inspection and business management systems. Now we have a team of dedicated trained experienced who take care the quality and timely supply. We are the preferred source manufacturer for cross-border e-commerce and trading companies and can provide relevant customers and peer manufacturers with applied solutions so that has won praise and trust from customers.

If you're looking for tablet binder copovidone cas 25086-89-9, please be free to place orders with our factory. We also support customized production for the famous brands' products. And if you need, the free sample is also available for quality checking.

Basic Info

  • Model NO.: 25086-89-9

  • Customized: Non-Customized

  • Suitable for: Elderly, Adult

  • Purity: >99%

  • Name: Copovidone

  • Function: Tablet Binder

  • Powder: Yes

  • Certification: ISO 9001

  • State: Solid

  • CAS: 25086-89-9

  • Molecular Formula: C30h45n3o9X2

  • Origin: Made in China

Product Description

Tablet Binder Copovidone CAS 25086-89-9
1. Quick Detail:

Product name:Copovidone
Other Name:Poly(1-vinylpyrrolidone-co-vinyl acetate); Aceticacid,ethenylester,polymerwith1-ethenyl-2-pyrrolidinone;aceticacidethenylester,polymerwith1-ethenyl-2-pyrrolidinone;aceticacidethenylestercopolymerwith1-ethenyl-2-pyrrolidinone;aceticacidvinylester,polymerwith1-vinyl-2-pyrrolidinone;copolyresinvinylketopyrrolidine/vinylacetate;copolyvidon;e335;e535
Molecular formula:C30H45N3O9X2
Leading  timewithin 24 hours upon receipt of payment
PackageDiscreet and Hidden package according to specific requirement
AppearanceWhite Powder
CertificationISO 9001
UsageCopovidone, an analog of povidone, is used as a tablet binder, a film-former, and as part of the matrix material used in controlled-release formulations.

2. Description:
 The Copovidone is a water-soluble organic polymer, and is a linear copolymer of vinyl N- (NVP) and vinyl acetate (VA). (PVP/VA)
Nature:Since the structure of and NVP is the structure of and VA, it has the properties of both PVP and PVAC. Compared the nature of the above three products, polyvidone retained the good PVP water solubility, adhesion and membrane, and than the PVP is relatively much lower water absorption and more broad solubility, better plasticity and stronger surface activity (Note: the vegetables on the surface of the water affinity than PVP).

Therefore, this product is a kind of fine tablet binder, which has the characteristics of high hardness and low brittleness, and can be used in the wet conditions. It is especially suitable for high dose, poor water solubility and water sensitive drug. 
3. Application:
1. Copovidone, an analog of povidone, is used as a tablet binder, a film-former, and as part of the matrix material used in controlled-release formulations. In tableting, copovidone can be used as a binder for direct compression and as a binder in wet granulation. Copovidone is often added to coating solutions as a film-forming agent. It provides good adhesion, elasticity, and hardness, and can be used as a moisture barrier.

2. Copovidone has better plasticity than povidone as a tablet binder, is less hygroscopic, more elastic, and better for film-forming applications than povidone. Copovidone is also used in cosmetics as a thickener, dispersant, lubricant, film-forming agent and binder. It is widely used in the food, cosmetic and pharmaceutical industry.

3. Copovidone is generally regarded as nontoxic. However, oral consumption of excessive quantities may produce stomach upset.  It has not been shown to be sensitizing to the skin. Animal studies in rats and dogs do not show significant toxicity with high dietary levels.

4. As tablet and granule, the adhesive can be used wet, dry granulation and direct compression method to complete, in most cases the dosage of micro gross preparation of 2% - 5%, general is about 3%, concentration of adhesive generally 5 ~ 10%. According to the different materials and auxiliary materials, water or alcohol and other solvents can be used as solvent.
When the direct compression method is used, the dosage is about 5%, which can be used as the auxiliary material, such as lactose, sorbitol, mannitol and microcrystalline cellulose, but it should pay attention to controlling the moisture content in the ingredients to maintain proper bonding. 

4. Application
1.Water soluble tablet binder:suitable wet or dry granulation and direct compression processes,improves particle compressibility.
2.Film-former:permeable film coating for tablet and sugar coatings to protect against splitting,decrease moisture sensitivity and provide good film adhesiveness,elasticity and hardness.
3.Porogenic agent:for use in taste-masking and component of the matrix material used in controlled-release formulation.
4.Solubilizing agents:for solid depersion processes to enhancing bioavailability and improve drug solubility.

5. Technical Testing Sheet    


AppearanceWhite powderComplies
K Value                                                                 25.4-34.230.9
PH value (1% in water)5.0-7.05.6
Monomer (VP+VA)                    ppm≤ 10<10
Nitrogen                                        %7.0-8.07.4
Heavy metal (as lead)                    %≤ 0.001< 0.001
Aldehyde   ppm≤ 500< 500
NVP       %≤ 0.200.09
Moisture      %≤ 5.03.62



If you're looking for 25086-89-9, please be free to place orders with our factory. We also support customized production for the famous brands' products. And if you need, the free sample is also available for quality checking.
We emphasize progress and introduce new solutions into the market each year for Pharmaceutical Excipient Croslinked Polymer Crospovidone. Our company insists on green production and scientific quality management, and has passed various quality management certifications. We encourage employees to be loyal to the company's business, hoping to establish a win-win strategy between the company and employees.
Hot Tags: 25086-89-9, factory, brands, customized, free sample, Polyplasdone, crospovidonum, high viscosity PVP, pill binder, film forming agent, PVP K90 solution


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