CAS NO.9003-39-8
Product type: Water-soluble polymer
Chemical name:Polyvinylpyrrolidone
USP/EP name:Povidone
INC/CTFA name:PVP
Molecular formula:(C₆H₉NO)n
Ingredients: PVP, water, thickener, etc.
Features: Transparent, high viscosity aqueous liquid.
PVP is a water-soluble polymer with high viscosity and the ability to form hydrogen bonds with a variety of compounds.
Characteristic
Water solubility: PVP is a highly water-soluble polymer that can form clear solutions in water and is miscible with many organic solvents. This makes it a versatile formulation ingredient.
Film-forming property: PVP has excellent film-forming properties and is widely used in products that require the formation of films or coatings, especially in the cosmetics and pharmaceutical fields.
Biocompatibility: PVP has good biocompatibility and low toxicity, making it suitable for pharmaceutical and personal care products and safe for the human body.
Hygroscopicity: PVP is a hygroscopic material that can absorb water, which has a moisturizing effect in skin care products.
Stability: PVP is stable over a wide pH range and has good chemical and thermal stability, making it suitable for a variety of formulation systems.
Specification
| DMF FILE NO. | 033506 | 033415 | 032698 | 033592 | |||||
| SUNVIDONE | K12 | K15 | K17 | K25 | K30 | K90 | |||
| Colour(5%in water)min | BY6,B₆ | BY6,B₆ | BY6,B₆ | BY6,B₆ | BY6,B₆ | BY₆,B₆ | |||
| K value | 10.2-13.8 | 12.8-17.3 | 15.3-18.4 | 22.5-27.0 | 27.0-32.4 | 81.0-97.2 | |||
| Impurity A,ppm max | 10 | 10 | 10 | 10 | 10 | 10 | |||
| Impurity B,%max | 3.0 | 3.0 | 3.0 | 3.0 | 3.0 | 3.0 | |||
| Formic Acid.%max | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | |||
| Peroxides,ppm max | 400 | 400 | 400 | 400 | 400 | 400 | |||
| Aldehyde,ppm max | 500 | 500 | 500 | 500 | 500 | 500 | |||
| Hydrazine,ppm max | 1 | 1 | 1 | 1 | 1 | ||||
Applications
1. Pharmaceutical Industry: PVP is widely used in the pharmaceutical industry as an excipient. It is used as a binder to hold tablets together, as a disintegrant to ensure rapid disintegration of tablets in the stomach, and as a solubilizer to enhance the dissolution of poorly soluble drugs. It is also used as a coating material to improve the appearance and stability of tablets.
2. Cosmetics and Personal Care: PVP is used in the formulation of creams, lotions, and gels due to its emulsifying, stabilizing, and solubilizing properties. It helps form a homogenous mixture of oil-based and water-based ingredients and can improve the spreadability and aesthetics of the final product.
3. Adhesives and Coatings: PVP and its derivatives are used as binders in a variety of adhesive and coating applications. PVP can be used in pressure-sensitive adhesives, such as those used in bandages, because of its stickiness and ability to form a strong bond with a variety of substrates. It is also used as a coating agent in paints, inks, and textiles due to its leveling properties and ability to form smooth films.
FAQ
1.What solvents can PVP be mixed with?
PVP has excellent solubility and is soluble in water and a variety of organic solvents, such as ethanol, isopropanol, etc. This makes it easy to use in cosmetics and pharmaceuticals and can form clear solutions or dispersions.
2. How does the molecular weight of PVP affect performance?
The molecular weight of PVP determines its physical properties, such as viscosity and solubility. The larger the molecular weight (such as PVP K90), the higher the viscosity of its solution, which is suitable for use as an adhesive or film-forming agent; PVP with a smaller molecular weight (such as PVP K30) is more suitable for use as a suspending agent or disintegrant.
3. What are the common forms of PVP?
PVP is usually supplied in the form of powder, solution or granules, and users can dissolve it in water or other solvents as needed and apply it to various products.
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